Therapeutic Drug Monitoring of Certolizumab Pegol-Can Real-World Data Translate to Clinical Practice?
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چکیده
منابع مشابه
Certolizumab pegol in rheumatoid arthritis: a review of Phase III clinical trials and its role in real-life clinical practice
TNF inhibitors (TNFi) have been in use in clinical practice for the treatment of rheumatoid arthritis (RA) since 1998. The first to be licensed was etanercept, a fusion protein consisting of two soluble p75-TNF-receptor domains and the constant fragment of immunoglobulin. Next was the chimeric mouse human antibody infliximab (the first TNFi to be trialed in man) and later the fully human antibo...
متن کاملCorrection to: Certolizumab Pegol in the Treatment of Psoriasis and Psoriatic Arthritis: Preliminary Real-Life Data
In the original publication, part Fig. 3b and c were interchanged. The correct versions are given below.
متن کاملCertolizumab Pegol in the Treatment of Psoriasis and Psoriatic Arthritis: Preliminary Real-Life Data
INTRODUCTION We present the results of real-life tests conducted in adults affected by psoriatic arthritis (PsA) with mild cutaneous involvement to evaluate the efficacy of certolizumab pegol (CZP), an anti-tumor necrosis factor-alpha agent approved in Europe for the treatment of rheumatoid arthritis and PsA. METHODS Assessments included an evaluation of the Psoriasis Area and Severity Index ...
متن کاملPregnancy Outcomes in Subjects Exposed to Certolizumab Pegol.
OBJECTIVE To provide information on pregnancy outcomes in women receiving certolizumab pegol (CZP). METHODS The UCB Pharma safety database was searched for pregnancies through to September 1, 2014. Reports for maternal and paternal CZP exposure were included and outcomes examined, and data on CZP exposure, pregnancy, comorbidities, and infant events were extracted by 2 independent reviewers. ...
متن کاملActive axial spondyloarthritis: potential role of certolizumab pegol
The axial spondyloarthropathies are a group of chronic inflammatory diseases that predominantly affect the axial joints. This group includes ankylosing spondylitis and nonradiographic axial spondyloarthropathy. While the pathogenesis of axial spondyloarthropathies is not clear, immunologically active tissues primarily include the entheses, ie, the areas where ligaments, tendons, and joint capsu...
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ژورنال
عنوان ژورنال: Crohn's & Colitis 360
سال: 2021
ISSN: 2631-827X
DOI: 10.1093/crocol/otab020